UCLA Health

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body’s key cancer-fighters, according to new UCLA research.

The study, conducted in mouse models and human cells and published in iScience, builds directly on earlier work from the same lab showing that creatine powers killer T cells in their battle against tumors. Now, the team has discovered that creatine also fuels dendritic cells, specialized immune cells that capture tumor fragments and direct killer T cells to attack. 

Most approved cancer immunotherapies work by targeting killer T cells directly, yet only about 20%-40% of patients respond to them. Bolstering the dendritic cells that train and activate T cells could potentially offer a way to bring the benefits of immunotherapy to more patients.

“Immunotherapy has shown remarkable promise, but it only works for a subset of patients,” said Lili Yang, the study’s senior author, a professor of microbiology, immunology and molecular genetics and a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. “What this study shows is that creatine doesn’t just help the T cells fighting cancer — it also energizes the entire infrastructure supports and guides them. That makes creatine a promising supplement to holistically support the immune response that modern immunotherapies depend on.”

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To complete your exchange or refund, we require a receipt, purchase order or other proof of purchase. Please note that without the aforementioned proof of purchase, we will not do an exchange or refund.

Exchange requirements

In order to return an order for an EXCHANGE, you must contact us first. 

Contact us at:

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An immediate response on next steps will be sent to you within 24-48hrs. 

The following criteria must be met to qualify for an exchange:
• Product is defective
• Product must be in original packaging
• Product must be unused In order to ensure the above criteria has been met, all returns will be inspected. If the product does not meet the listed criteria, we reserve the right not to issue an exchange. Perishable goods are completely exempt from being returned.

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An immediate response on next steps will be sent to you within 24-48hrs. 

Sale and clearance items

Only regular priced items may be exchanged or refunded, unfortunately, sale or clearance items cannot be exchanged or refunded.

Shipping items

In order to return an order for an EXCHANGE, you must contact us first.

Returns for exchanges must include the listed requirements, and can be mailed to: 1615 Lakes Pkwy, Suite C, Lawrenceville, GA 30043. You will be responsible for paying for the shipping costs with regard to the items that you wish to exchange. We will not refund the shipping costs.

You must take care to ensure that the goods are properly packaged so that they will not be damaged while in transit. If the product is found damaged or used beyond what it takes for us to reasonably inspect it, then we may reject an exchange.

In order to return an order for a REFUND, you must contact us first.

Returns for refunds must include the listed criteria requirements, and can be mailed to: 525 Coronel Pl., Santa Barbara, CA 93101. You will be responsible for paying for the shipping costs with regard to the items that you wish to refund. We will not refund the shipping costs.

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If you would like to contact us concerning any matter relating to our EXCHANGE and REFUND Policies, you may send an email to smartlifesups@gmail.com.

This document was last updated on 09/13/22.